GeneTether is an early stage biotechnology company developing improved gene editing technologies using Crispr/Cas, TALEN, and Zinc-Finger nucleases for human therapeutic applications. We are developing an approach that gives the DNA repair-templates the same “address” as the DNA strand breaks, ensuring their presence when needed for gene editing. This could improve gene editing efficiencies by over 100x while reducing unintended unwanted DNA damage and mutation.
Geoffrey Sargent, PhD is founder and CEO. Geoff has over 28 years in biotech and academia working in the fields of DNA damage, DNA repair, and DNA recombination in mammalian cells. He has led teams developing gene editing technologies in biotech and used a precursor technology to Crispr/Cas9, TALEN, and Zinc-Fingers to study the repair of DNA double strand breaks in mammalian cells.