Events
QB3 Webinar: Arnold Kriegstein, UCSF
Talk description to come.
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About the Speaker
Arnold Kriegstein, MD, PhD is the John Bowes Distinguished Professor in Stem Cell and Tissue Biology and founding director of the Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research at UCSF.
Dr. Kriegstein’s research focuses on the way in which neural stem and progenitor cells produce neurons in the embryonic brain. His lab found that radial glial cells, long thought to simply guide nerve cells during migration, are neuronal stem cells in the developing brain. He also described a class of intermediate precursor cells produced by radial glia, suggesting a new mechanism for the generation of cell diversity. Recently, he has focused on the developing human brain and identified a radial glia-like progenitor cell in the outer subventricular zone that contributes to the huge expansion of neuron number that characterizes human cerebral cortex.
Dr. Kriegstein received his BA from Yale University and his MD and PhD degrees from New York University in 1977 where his thesis advisor was Dr. Eric Kandel. He subsequently completed Residency training in Neurology at the Brigham and Women’s Hospital, Children’s Hospital, and Beth Israel Hospital in Boston. He has held academic appointments at Stanford University, Yale University, and Columbia University. In 2004 he joined the Neurology Department at the University of California, San Francisco.
Dr. Kriegstein’s own research focuses on the way in which neural stem and progenitor cells in the embryonic brain produce neurons, and ways in which this information can be used for cell based therapies to treat diseases of the nervous system. His lab found that radial glial cells are neuronal stem cells in the developing brain, and also identified a second type of precursor cell produced by radial glial cells that is responsible for generating specific neuronal subtypes. He has recently begun to characterize the progenitor cells within the developing human brain, to determine the genetic profiles of specific progenitor populations, and to explore how these cells contribute to the huge expansion of neuron number that characterizes human cerebral cortex.
