Events

QB3 Symposium: Systemic Health Regulated by the Ovarian Pacemaker

An auditorium full of people listening to a scientist talk at the podium

Background

While often discussed through the lens of fertility and menopause, the ovaries play a much broader role in regulating whole-body health—shaping metabolism, cardiovascular function, bone density, immune regulation, and brain aging. This becomes especially clear after menopause, when the risks for age-related diseases — including cardiovascular disease, dementia, osteoporosis, and metabolic diseases — rise significantly.

Yet we still lack a complete understanding of what drives ovarian aging and how it contributes to systemic decline. Hormone therapy remains the primary clinical option, but innovation has been limited for decades. This is a major opportunity for new diagnostics and treatments that target the ovaries themselves.

Advances in single-cell and spatial sequencing, organoid and model systems, and clinical studies are now accelerating progress, revealing new paths for early intervention and therapeutic development. This convergence of scientific opportunity and unmet need inspired QB3 to focus this year’s symposium on ovarian health and the systemic consequences of ovarian aging.

Goals

• Explore the role of the ovaries as regulators of systemic health and aging

• Highlight emerging discoveries and innovation in the field

• Foster connection between basic researchers, industry leaders, investors, and startup founders

• Identify emerging opportunities and motivate translation of cutting-edge discoveries into impactful therapies

Audience

We are bringing together industry and academic scientists; potential funders; and companies, from startups to big pharma, committed to the mission of understanding ovarian health and its impact on systemic health over time.

Venue

All sessions will be held in the auditorium at Bakar Bio Labs, located at 2625 Durant Ave., Berkeley, CA 94720. Followed by a reception in the Bakar Bio Labs courtyard.

Sponsored By

Agenda

8:00-8:30 AM | Arrival and Registration

  • Check-in, light breakfast, networking

8:30 AM | Welcome and Opening Remarks by David Schaffer (Professor, UC Berkeley, & Director of QB3 & Bakar Labs)

8:40 AM Session Chair: Lin He (Professor, UC Berkeley)

8:45 AM | Jennifer Garrison (Neuroscientist, Women’s Health Researcher, Entrepreneur): Reframing Female Health & Aging

9:05 AM | Francesca Duncan (Professor, Northwestern and Buck Institute): Transforming Ovarian Aging Mechanisms into Actionable Therapeutic Targets

9:25 AM | Laura Sanchez (Professor, UC Santa Cruz): Tapping into Unique Samples for Potential Ovarian Cancer Screening Applications

9:45 AM | Panel Discussion and Q&A

10:00 AM | Networking Break

  • Coffee and refreshments

10:20 AM Session Chair: Nina Kosaric (Executive Director & Site Head, Lilly Gateway Labs)

10:25 AM | Diana Laird (Professor, UCSF): Aging and Rejuvenation of the Ovary

10:45 AM | Ashley Abel (Co-founder and CEO, Metri Bio): Reimagining Endometriosis Drug Discovery

10:55 AM | Amander Clark (Professor, UCLA): Creating Ovarian Cells from Stem Cells

11:15 AM | Ivana Muncie-Vasic (Founder & CEO, Vitra Labs): In Vitro Activation and Development of Primordial Follicles

11:25 AM | Panel Discussion and Q&A

11:40 AM | Lunch

12:40 PM Session Chair: Saul Villeda (Associate Professor, UCSF)

12:45 PM | Emily Jacobs (Professor, UC Santa Barbara): Dynamic Endocrine Modulation of the Nervous System

1:05 PM | Dena Dubal (Professor, UCSF): Ovarian Contributions to Longevity and Brain Health

1:25 PM | Marcelle Cedars (Professor, UCSF): Ovarian Aging and Cardiovascular Risk

1:45 PM | Panel Discussion and Q&A

2:00 PM | Afternoon Break

2:20 PM Session Chair: Tim Luker (Vice President, Lilly Ventures)

2:25 PM | Ugur Eskiocak (Co-founder and CEO, Voro Therapeutics): Tumor-Activated PrimeBody Platform Unlocks the Safe and Effective Delivery of Potent Biologics Beyond the Reach of Conventional Approaches

2:35 PM | Irene Chen (Assistant Professor, UC Berkeley and UCSF): Harnessing AI to Bridge Gaps in Women’s Health Care

2:55 PM | Naseem Sayani (VC Investor & Ecosystem Builder): Where Will the Next $100 Billion Come from?

3:05 PM | Panel Discussion and Q&A

3:20 PM | Afternoon Break

3:40 PM | Panel Discussion

Moderator: Risa Stack, Co-Founder, BEVC

Jamie Justice, Executive Director, XPRIZE Healthspan

Lisa Suennen, Managing Partner, American Heart Association Ventures

Michal Elovitz, CEO, Nuttall Women’s Health

Alice Zheng, Partner, Foreground Capital

4:30 PM | NFX FAST Award Presentation

4:45-6:00 PM | Networking Reception

This symposium is directed by Katarina Klett, Director of Research Translation at QB3, with support from the QB3 events and programs team.

If you have any questions about this event, please email Katarina.

Planning Committee

Lin He, PhD

Professor of Molecular Cell Biology, UC Berkeley

Katarina Klett, PhD

Director of Research Translation

Diana Laird, PhD

Professor, UCSF

Widya Mulyasasmita, PhD

BEVC, Managing Partner

Gloria Wu, MD, PhD

Senior Director, Lilly Ventures

Speakers & Session Chairs

Ashley Abel, PhD

CEO of Metri Bio

Marcelle Cedars, MD

Professor and Director of the Division of Reproductive Endocrinology, UCSF

Irene Chen, PhD

Assistant Professor, UCSF, UC Berkeley

Amander Clark, PhD

Professor of Molecular Cell and Developmental Biology, UCLA

Dena Dubal, MD, PhD

Professor of Neurology, UCSF

Francesca Duncan, PhD

Associate Professor, Northwestern University and Buck Institute

Michal Elovitz, MD

CEO of Nuttall Women’s Health

Ugur Eskiocak, PhD

CEO of Voro Therapeutics

Jennifer Garrison, PhD

Neuroscientist, Women’s Health Researcher, Entrepreneur

Emily Jacobs, PhD

Professor of Neuroscience, UCSB

Jamie Justice, PhD

Executive Director, XPRIZE Healthspan

Nina Kosaric, PhD

Executive Director, Site Head, Lilly Gateway Labs

Tim Luker, PhD

Vice President, Lilly Ventures

Ivana Muncie-Vasic, PhD

CEO of Vitra Labs

Laura Sanchez, PhD

Professor of Chemistry and Biochemistry, UCSC

Naseem Sayani

VC Investor and Ecosystem Builder

Risa Stack, PhD

Co-founder, BEVC

Lisa Suennen

Managing Partner, American Heart Association Ventures

Saul Villeda, PhD

Associate Professor of Anatomy, UCSF

Alice Zheng, MD, MBA, MPH

Partner, Foreground Capital