RUMI Scientific


RUMI Scientific
San Francisco, CA

Residents
RUMI Scientific

RUMI Scientific seeks to revolutionize the landscape of drug discovery through its proprietary human stem cell technology that uses single-cell, time-lapse imaging and customized analytic tools to inexpensively and more effectively identify treatments for human genetic diseases.
With RUMI’s micropattern technology, human embryonic stem cells self-organize to generate a signature defined by geometry and size, driven by processes that occur in vivo as the cells differentiate to give rise to different human cell types. Many disease-causing mutations will change the signature. The use of isogenic cell lines recapitulating mutations that are causal to human diseases can be applied to high-throughput screens to identify compounds that revert the disease signature back to normal. This technology allows a high-resolution evaluation of cellular behaviors comparatively between normal and disease state, providing an opportunity to perform “clinical trials on human micropatterns”.