Prellis


Prellis
San Francisco, CA

Residents, Venture-Backed
Prellis

Prellis Biologics is developing technology to build transplantable human organs and tissues. Our aim is to address the organ shortage and provide human tissues to streamline the development of therapeutics. The first transplantable human tissues Prellis Biologics is working to develop are the insulin secreting units of the pancreas, Islets of Langerhans. A renewable, safe source of Islets of Langerhans will provide an option to millions of people living with Type 1 Diabetes Mellitus (T1DM). An islet transplant may allow T1DM patients to become insulin independent thereby avoiding daily injections and finger pricks for monitoring and regulating dangerous blood sugar swings. In addition, our company has developed a printing process to create human Lymph Node Organoids (LNO), capable of immune responses and generation of human antibodies, bypassing the need for antibody development in animals. In our proof-of-concept studies, our scientists created 14 novel class-switched human IgG antibodies that are reactive to the Zika Virus in less than 6 weeks. By engineering human tissues in the laboratory for rapid therapeutics development, our technology will streamline bench-to-bedside research and efficiently address emerging disease outbreaks. Prellis Biologics was co-founded in 2016 by Dr. Melanie Matheu and Dr. Noelle Mullin, two PhDs with a passion for bringing engineering and biology together to solve unmet medical needs.