About
about
Research and innovation across the full spectrum of biotech
Overview
QB3 is one of four California Institutes for Science and Innovation, a multicampus operation with departments on the UC campuses at Berkeley, San Francisco, and Santa Cruz. QB3’s domain is the “quantitative biosciences,” a multidisciplinary area encompassing the study of biology using techniques and technology derived from chemistry, physics, and computer science.
QB3 supports early-stage commercialization in biotech and pharma, and conducts basic and applied research. Commercialization programs, including incorporation, mentorship, and the Bakar Labs incubator, are largely run out of the QB3-Central office, currently at UC Berkeley. QB3 entrepreneurial programs welcome participants and founders from academia and industry, who need not have affiliations with UC.The institute was founded with the goal of laying the foundations of future industry in California.
QB3-Central also coordinates collaborative research bringing together scientists from all three campuses. The three campus divisions operate core facilities and administer research programs. See Research for details.
Our Team
The people who make things happen
Our core team, who run our operations across the spectrum from basic research to startup support. We’re always open to new ideas and initiatives.
Spotlight
Startup Alums
We’ve supported biotech startups since 2005 with incubator space, programming, and VC investment.
4D Molecular Therapeutics
4D Molecular Therapeutics develops gene therapies for patients with eye, lung, and heart conditions. The company is currently running four clinical trials, for Fabry disease, X-linked retinitis pigmentosa, and choroidemia, and recruiting for two: for cystic fibrosis and age-related macular degeneration. 4D was incorporated in 2013 through QB3 and incubated at QB3@953 (now an MBC Biolabs location). QB3 executive director David Schaffer is a co-founder.
Caribou Biosciences
Caribou Biosciences, a spinoff from the UC Berkeley lab of Nobel laureate Jennifer Doudna, develops off-the-shelf CRISPR genome-edited cell therapies for patients with devastating diseases. The company has two trials in progress of CAR-T cell therapies for multiple myeloma and non-Hodgkin lymphoma. Caribou was co-founded by CEO Rachel Haurwitz (PhD, UC Berkeley), incorporated through QB3, incubated at two QB3 facilities, and was an early portfolio company of QB3-affiliated VC firm Mission Bay Capital.
Pivot Bio
Pivot Bio manufactures living microbial-based nitrogen fertilizers, produced by fermentation. This replaces the energy-intensive Haber-Bosch process, thereby reducing greenhouse emissions. The technology also eliminates toxic fertilizer runoff. Pivot introduced the world’s first nitrogen-producing microbes to U.S. farmers in 2018. Since that time the company has introduced multiple microbial nitrogen products for wheat, sorghum and other small grains in addition to its flagship product for corn. Pivot was co-founded by CEO Karsten Temme (PhD, UC Berkeley) and CTO Alvin Tamsir (PhD, UCSF) and incubated at the QB3 Garage at UCSF.
Bolt Threads
Bolt Threads develops high-performance materials through sustainable, green processes. Their initial product was MicrosilkTM, inspired by spider dragline silk and produced through synthetic biology. Founded by CEO Dan Widmaier (PhD, UCSF), CTO David Breslauer (PhD, UC Berkeley, and Ethan Mirsky (PhD, UCSF), Bolt incubated for several years at the QB3 Garage at UCSF and was one of the Fund I investments by QB3-affiliated VC firm Mission Bay Capital. Further products include MyloTM mushroom leather and B-SilkTM protein, an alternative to silicone elastomers.
Past and Current
Companies
- Alector
- Ablexis
- MyNurse
- Bikanta
- Osprey Pharmaceuticals USA
- Catalia Health
- ReCreate Bio
- Orb
- Andes Biotechnologies
- XP Health
- GenEdit
- Principia Biopharma
- Unnatural Products
- Palisade Therapeutics
- Mekonos
- 11 Health
- HPI Biosciences
- Invenio
- Serotiny
- Atreca
- Tiatros
- Ray Therapeutics
- Calyx
- Riffyn
- Madorra
- Regel Therapeutics
- Xip
- Novome Biotechnologies
- Endometrics
- Perlara
- Avisi Technologies
- Redwood Bioscience
- Tueo Health
- Teralytic
- Laguna Health
- Felix Biotechnology
- Emme
- Chrono Therapeutics
- Scribe Biosciences
- Indee Labs
- Lygos
- Sprint Synthesis
- Darmiyan
- BioChoric
- Evren Technologies
- Prellis Biologics
- Nano Precision Medical
- Allotrope Medical
- OneSkin
- PuraCath Medical
- Survey Genomics
- Valitor
- Shasqi
- Revitope Oncology
- Alessa Therapeutics
- Therini Bio
- AOBiome
- SyntheX
- Siolta Therapeutics
- DotLab
- Glycomine
- NeuroSave
- Chameleon Biosciences
- Delve Therapeutics
- Minutia
- Catena Biosciences
- Blumio
- Third Pole
- Engine Biosciences
- Evolva
- Correlia Biosystems
- mFluiDx
- Circle Pharma
- iSono Health
- SillaJen
- Cor
- Sampling Human
- Script Health
- Scuba Probe Technologies
- HepaTx
- Bloomlife
- Concha Labs
- Exogen Bio
- Combinati
- Zymergen
- Noleus Technologies
- Perceptive Navigation
- General Automation Lab Technologies
- Trace Genomics
- Dextera Biosciences
- iMicrobes
- OncoSynergy
- Xcell Biosciences
- Solidus Bioscience
- Guided Clarity
- AccuraGen Holdings
- Razzberry
- Scaled Biolabs
- Ria Health
- VenomYx
- KuriBio
- Signum Surgical
- Invenio Imaging
- imvaria
- REGiMMUNE
- Valera Health
- Telo Therapeutics
- Encoded Therapeutics
- Tangible Science
- Cibiem
- Abreos Biosciences
- Precision NanoSystem
- Phyla
- Replace Therapeutics
- Applaud Medical
- Insamo
- Glyphic Biotechnologies
- Karuna Labs
- Miroculus
- Foodsmart
- Zoetic Data
- YourChoice Therapeutics
- InnoVein
- AEENA Dx
- Mekonos
- DABOmics
- Suono Bio
- Gemmus Pharma
- Intelligent Implants
- Elenae
- Silver Creek Pharmaceuticals
- Sublime Therapeutics
- Fauna Bio
- pH Pharma
- Perlumi
- Olfa Thera
- Aucta Technologies
- Luma Therapeutics
- CV Ingenuity
- Umaro Foods
- Jennerex Biotherapeutics
- Mae
- Globavir
- Raydiant Oximetry
- Genetic Foresight
- Panazee
- Safely Health
- Samay
- Mission Barns
- Safe H2O
- ViewPoint Therapeutics
- Cyclica
- iPierian
- Auricle
- ChemiSense
- Photoswitch Biosciences
- Lucira Health
- Alio
- Tunitas Therapeutics
- SeaChange Pharmaceuticals
- Effector Therapeutics
- Cell Design Labs
- ARIZ Precision Medicine
- Inapill
- Potrero Medical
- Moving Analytics
- AnimalBiome
- Motum
- Nodexus
- Droplet
- Profluent Bio
- Via Nova Therapeutics
- Siris Medical
- ApniCure
- Verinomics
- Epalex
- Digbi Health
- Opus Bio
- Bolt Threads
- Meissa Vaccines
- UroDev Medical
- Shade
- Namocell
- G-Tech Medical
- TeselaGen
- Omni Therapeutics
- Aromyx
- SiteOne Therapeutics
- 712 North
- Pharmajet
- Ontera
- Invitae
- Nobell Foods
- Calithera Biosciences
- Novela Neurotech
- Kenota Health
- Black Sheep Foods
- Siren Care
- Aura Health
- Visana Health
- Ciznor
- Sequenta
- Bisu
- Vicinitas Therapeutics
- Delinia
- Channel Medsystems
- Omniox
- Diadem Biotherapeutics
- Knowledge Synthesis
- Wildtype
- CureMetrix
- Zephyrus Biosciences
- CellSight Technologies
- Cala Health
- HOPO Therapeutics
- InkSpace Imaging
- Ribogenics
- Catena Biosciences
- Cypre
- Assembly Biosciences
- Delpor
- GigaGen
- Minutia
- LogicInk
- Symic Biomedical
- Genesis DNA
- DiscoDisc Bio
- Arterys
- Novonate
- Spora Health
- MiNDERA Corporation
- Provenance Biopharmaceuticals
- Lypro Biosciences
- Bell Biosystems
- Intact Therapeutics
- Privail
- Aquinox Pharmaceuticals
- Dropprint Genomics
- InnaMed
- Allopartis
- Multerra Bio
- Thea Health
- Amarantus BioSciences
- ResVita Bio
- Pendulum Therapeutics
- Eidos Therapeutics
- CinderBio
- 4D Molecular Therapeutics
- BabyNoggin
- MD Ally
- Evercrisp
- Iris Medicine
- NeuraLace Medical
- Obsidio
- True North Therapeutics
- Aikium
- EYSZ
- Fullmoon Sensors
- Blueprint Genetics
- Tierra Biosciences
- Alpha Medical
- Satoris
- Fluxion Biosciences
- Aluna
- Siluria Technologies
- Nosis Bio
- Radar Therapeutics
- Addition Therapeutics
- Mission Bio
- Coagulant Therapeutics
- Reflexion Pharmaceuticals
- Zenflow
- EvolveMol
- Velano Vascular
- BillionToOne
- Aurora Bio
- Seven Starling
- GraphWear Technologies
- Sontina Medical
- Sano
- Concentric Analgesics
- Liquidity Nanotech
- GT Medical Technologies
- Kilimanjaro Energy
- Caribou Biosciences
- Lully
- OOTify
- Ripple Foods
- River Health
- Fountain Therapeutics
- Fibralign Corporation
- Pivot Bio
- Axent Biosciences
- Vivace Therapeutics
- Arcadia Science
- Deep Blue Medical Advances
- Pionyr Immunotherapeutics
- CellFE
- Vellum Biotechnologies
- Carmot Therapeutics
- Kiverdi
- MetaMixis
- Ohayo Valley
- Zeto